
It is a significant reduction of fat in the legs, arms, buttocks, and face, which can make muscles and veins very visible. In the face, it primarily occurs in the malar regions (Bichat's fat) and pre-temporal areas.
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These changes cause a great psychological impact, by provoking a cadaverous appearance on the face and revealing the diagnosis, which most patients wish to keep confidential. This loss of adipose tissue can be caused by both the natural aging process and different systemic diseases such as Lupus and Multiple Sclerosis, fatty atrophies resulting from trauma, or, mainly, as a response to the use of antiretroviral medications for HIV treatment.
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As a treatment to correct the skin furrows and depressions produced by lipoatrophy, facial filling with subdermal implants, fillers, and even fat grafting is recommended, always performed by a specialist doctor.
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